| CAS Number: | 64987-85-5 |
|---|---|
| Product Code: | ARL4001 |
| Molecular Formula/Molecular Weight: | / 334.32 |
| Purity: | 98% |
| HSN Number: | 29224990 |
Note: For research use only, not for direct human use.*
| Pack Size | Unit Price | Stock in Mumbai WH | Stock in Hyderabad WH | Quantity |
|---|
Description : SMCC is a heterobifunctional crosslinker that appears as an off-white or white solid. It is a non-cleavable and membrane-permeable linker used in bioconjugation, particularly for creating antibody-drug conjugates (ADCs). SMCC contains both an amine-reactive NHS ester and a sulfhydryl-reactive maleimide group.
| Appearance | White to almost white powder to crystals |
| Purity (GC) | min. 98% |
| Confirms Structure | NMR |
| Melting Point | 180-182 °C |
| Solubility | Soluble in DMF |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | −20°C |
| Conditions to Avoid | Moisture Sensitive |
| Storage Condition | Store under inert atmosphere |
| Packaging and Container | Glass bottle |
Pictogram :
|
| Safety regulations emphasize preventing skin and eye contact, inhalation of dust or aerosols, and exposure to sources of ignition. Appropriate personal protective equipment (PPE) like gloves, protective clothing, and respiratory protection (depending on exposure) is essential. |
SMCC is a crosslinker primarily used in the development of antibody-drug conjugates (ADCs). It acts as a bridge between an antibody and a drug payload, forming a stable covalent bond. This stable bond ensures the drug remains attached to the antibody until it is internalized by the target cell.
This is a sample COA and may not represent a recently manufactured lot of the product.